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Search Results for " trp channel "

20

Compounds

Cat No. Product Name Synonyms Targets
T40042 Evifacotrep TRP/TRPV Channel
Evifacotrep is a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100). Evifacotrep can be used for the research of neurological diseases.
T22124 Oleoyl Serotonin TRP/TRPV Channel
Oleoyl Serotonin is an antagonist of hTRPV1 with an IC50 of 2.57 μM.
T7177 Capsazepine Apoptosis , TRP/TRPV Channel
Capsazepine is an antagonist of TRPV1 receptor ( IC50 : 562 nM). Capsazepine blocks the painful sensation of heat caused by capsaicin (the active ingredient of chilli pepper) which activates the TRPV1 ion channel. It is ...
T12514 Podocarpic acid Others , TRP/TRPV Channel
Podocarpic acid is a natural product and a novel TRPA1 activator.
T6S1684 8-Gingerol Antioxidant , Antibacterial , TRP/TRPV Channel
1. 8-Gingerol has antioxidant activity. 2. 8-Gingerol has antimycobacterial activity. 3. 8-Gingerol could be used as an effective skin-whitening agent. 4. 8-Gingerol shows antipyretic and anti-inflammation characteristic...
T6617 Optovin TRP/TRPV Channel
Optovin is a TRPA1 activator, which is reversibly photoactivated.
T2807 Caffeic Acid Lipoxygenase , Endogenous Metabolite , TRP/TRPV Channel
Caffeic Acid is an orally bioavailable, hydroxycinnamic acid derivative and polyphenol, with potential anti-oxidant, anti-inflammatory, and antineoplastic activities.
T2298 ML204 TRP/TRPV Channel
ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
T10537 BI-749327 TRP/TRPV Channel
BI-749327 is a high selectivity and orally bioavailable antagonist of TRPC6 (IC50s: 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6).
T5698 TRPM8 antagonist 2 TRP/TRPV Channel
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist with an IC50 of 0.2 nM. TRPM8 antagonist 2 is used in the research of neuropathic pain syndromes.
T6660 SB-705498 TRP/TRPV Channel
SB705498 is a TRPV1 antagonist for hTRPV1. SB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.
T7430 AM-0902 TRP/TRPV Channel
AM-0902 is a potent and specific TRPA1 antagonist (IC50s: 71/131 nM for rTRPA1 and hTRPA1).
T16763 RN-1747 TRP/TRPV Channel
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 agonists (EC50: 0.77 μM, 4.0 μM, and 4.1 μM for hTRPV4, mTRPV4, and rTRPV4 respectively). RN-1747 also antagonizes TRPM8 (IC50: 4 μM...
T15628 JT010 TRP/TRPV Channel
JT010 is an effective agonist of TRPA1 (EC50 = 0.65 nM).
T9709 TRPM8 antagonist 3 TRP/TRPV Channel
TRPM8 antagonist 3 is a blocker of TRPM8 (IC50 = 11 nM).
T10300 AMG2850 TRP/TRPV Channel
AMG2850 is a potent, orally bioavailable, and selective antagonist of transient receptor potential melastatin 8 (TRPM8).
T4680 HC-067047 HC067047 TRP/TRPV Channel
HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .
T5640 GSK2193874 TRP/TRPV Channel
GSK2193874 was identified as a selective, orally active TRPV4 blocker.
T12941 SN 2 TRP/TRPV Channel
SN 2 is a novel and potent TRPML3 ion channel activator(EC50 of 1.8±0.13 μM).
T19723 AMTB hydrochloride AMTB TRP/TRPV Channel
AMTB hydrochloride (AMTB HCl) is a novel TRPM8 channel blocker and is effective for pain and urinary diseases. AMTB can act on the bladder afferent pathway to attenuate the bladder micturition reflex and nociceptive refl...
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